Mesothelioma Clinical Trials

One of the most exciting areas of research in the fight against mesothelioma comes in the form of clinical trials. These trials evaluate the safety and effectiveness of new drugs and treatments for all types of mesothelioma and can help patients not only live longer after a mesothelioma diagnosis but may help to combat symptoms or reduce the size of tumors overall. Clinical trials are not open to all mesothelioma patients but instead will have a number of eligibility guidelines depending on the type of trial being conducted and what the new drug or treatment is supposed to do. Many clinical trials for mesothelioma allow patients to apply for entry into the trial, but access is never guaranteed. Nonetheless, these trials can be a great source of not only hope for the future, but potential benefits for those currently affected by mesothelioma.

Clinical Trial Phases

Mesothelioma clinical trials are broken into three phases. In phase I, only a small number of patients are given entry and the trial is typically aimed at determining how a new drug or treatment should be administered. Drugs or treatments that have just been developed and have no real-world track record will fall under phase I. Phase II clinical trials are meant to gather more data about how well the drug or treatment works as well as assess any safety risks that exist when the drug is taken over time. Phase III trials are designed to take the most promising drugs and treatments from phase II trials and compare them against established methods of care to determine their effectiveness. In some cases, new treatments or medication will be used in conjunction with existing methods to see if there is an increase in efficacy.

Clinical Trails Requirements

Most mesothelioma clinical trials will have an eligibility requirement depending on what the study is looking to accomplish. This requirement may be based on age, sex, type of mesothelioma or the stage of the cancer - not all patients can be given access to all trials. Nonetheless, there are a large number of trials currently being conducted in the United States for those patients that are interested. Included in this is a phase III study of the effectiveness of Suberoylanilide Hydroxamic Acid (SAHA) against advanced pleural mesothelioma when compared with a placebo, and phase II study of the drug Eloxatin in combination with chemotherapy in fighting all types of mesothelioma. Every year, new studies are developed and new trials conducted - while not every trial will be available to all patients, there is always new research on the horizon.

While the exact cause and therefore cure-all treatment for mesothelioma has not yet been found, clinical trials are helping to give doctors more information and patients a better chance at survival. These trials represent the leading edge of mesothelioma research and can help give hope to anyone with this form of cancer, no matter its stage. For more information, contact us today and learn about clinical trials in your area, doctors sponsoring them and how to qualify.